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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence

Cited:

FLOW

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.11 mg/ml

Product Specifications

Immunogen

A synthetic peptide made to an internal portion of the human ABCB5 protein (between residues 450-500) [UniProt Q2M3G0]

Localization

Cell membrane; Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ABCB5 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: ABCB5 Antibody [NBP1-77689] - ABCB5 antibody was tested in A431 cells with FITC (green). Nuclei were counterstained with DAPI (blue).

Applications for ABCB5 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100
Application Notes
This ABCB5 antibody is useful for Immunocytochemistry/Immunofluorescence.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS and 30% Glycerol

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.11 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ABCB5

The ATP-binding cassette sub-family B member 5 (ABCB5) is an ABC transporter and PGP member. It is highly expressed in skin and in malignant melanoma. When two abnormal growths of tissues occur, resulting in multiple malignancies, ABCB5 is often highly expressed. This elevated expression in tumor cells can indicate a propensity towards therapeutic failure in many cases. Analysis of ABCB5 concentrations in tumors has been suggested as a fairly dependable qualitative biomarker for assessing the malignancy of melanomas.

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 5

Alternate Names

ABCB5 P-gp, ABCB5alpha, ABCB5beta, ATP-binding cassette protein, ATP-binding cassette sub-family B member 5, ATP-binding cassette, sub-family B (MDR/TAP), member 5, EC 3.6.3, EC 3.6.3.44, EST422562, P-glycoprotein ABCB5

Entrez Gene IDs

340273 (Human)

Gene Symbol

ABCB5

UniProt

Additional ABCB5 Products

Product Documents for ABCB5 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ABCB5 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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