Aminopeptidase N/CD13 Antibody (RM403)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23461

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-23461
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM403

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Aminopeptidase N/CD13 Antibodies »

Product Summary for Aminopeptidase N/CD13 Antibody (RM403)

Immunogen

A peptide corresponding to residues near the C-terminus of human Aminopeptidase N/CD13 (Uniprot#: P15144)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Aminopeptidase N/CD13 Antibody (RM403)

Aminopeptidase N/CD13 Antibody (RM403)

Aminopeptidase N/CD13 Antibody (RM403) [NBP3-23461] -

Aminopeptidase N/CD13 Antibody (RM403) [NBP3-23461] - Immunohistochemical staining of formalin fixed and paraffin embedded human liver section
Aminopeptidase N/CD13 Antibody (RM403)

Western Blot: Aminopeptidase N/CD13 Antibody (RM403) [NBP3-23461] -

Western Blot: Aminopeptidase N/CD13 Antibody (RM403) [NBP3-23461] - Western Blot of HepG2 cells lysate using Clone RM403) at a 1:2000 dilution.

Applications for Aminopeptidase N/CD13 Antibody (RM403)

Application
Recommended Usage

Immunohistochemistry

1:100-1:200

Western Blot

1:1000-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Aminopeptidase N/CD13

Alanine aminopeptidase (CD13) is expressed on the majority of peripheral blood monocytes and granulocytes. CD13 is also expressed by the majority of acute myeloid leukemias, chronic myeloid leukemias in myeloid blast crisis, a smaller percentage of lymphoid leukemias and myeloid cell lines. CD13 is also found in several types of non hematopoietic cells such as fibroblasts and endothelial cells and in a soluble form in blood plasma. CD13 is not expressed on B cells, T cells, platelets or erythrocytes. In the mouse, CD13 is a non-covalently linked homodimer of approximately 150kD subunits expressed by a variety of cells including monocytes, macrophages, dendritic cell and veiled cells. CD13 plays a role in biologically active peptide metabolism, in the control of growth and differentiation, in phagocytosis and in bactericidal/tumoricidal activities. CD13 also serves as a receptor for human coronaviruses.

CD13 is commonly used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. Therefore, CD13 antibodies are useful tools for cancer and renal disorder research.

Alternate Names

Aminopeptidase M, ANPEP, APN, CD13, gp150, PEPN

Gene Symbol

ANPEP

Additional Aminopeptidase N/CD13 Products

Product Documents for Aminopeptidase N/CD13 Antibody (RM403)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Aminopeptidase N/CD13 Antibody (RM403)

[Public Notes]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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