beta-Arrestin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21381

Novus Biologicals, part of Bio-Techne
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NBP3-21381-100ul
NBP3-21381-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all beta-Arrestin 2 Antibodies »

Product Summary for beta-Arrestin 2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FVLMHPKPHDHIPLPRPQSAPTPTPPLP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for beta-Arrestin 2 Antibody

Immunocytochemistry/Immunofluorescence: beta-Arrestin 2 Antibody [NBP3-21381] -

Immunocytochemistry/Immunofluorescence: beta-Arrestin 2 Antibody [NBP3-21381] -

Staining of human cell line HEL shows localization to nucleoplasm & plasma membrane.

Applications for beta-Arrestin 2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: beta-Arrestin 2

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Alternate Names

ARB2, ARR2, ARRB2, betaArrestin 2

Gene Symbol

ARRB2

Additional beta-Arrestin 2 Products

Product Documents for beta-Arrestin 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for beta-Arrestin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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