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Fibroblast Activation Protein alpha/FAP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14320

Novus Biologicals, part of Bio-Techne
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NBP3-14320

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (94%), Equine (100%), Monkey (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from extracellular domain of human Fibroblast Activation Protein alpha/FAP.

Epitope

Extracellular Domain

Reactivity Notes

Expected reactivity based on percent sequence identity: Canine (88%), Rat, Bat (82%)

Specificity

Human Fibroblast Activation Protein alpha/FAP. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Fibroblast Activation Protein alpha/FAP Antibody

Immunohistochemistry-Paraffin: Fibroblast Activation Protein alpha/FAP Antibody [NBP3-14320] - Immunohistochemistry of formalin-fixed, paraffin-embedded human skin, hair follicle, after heat-induced antigen retrieval.

Applications for Fibroblast Activation Protein alpha/FAP Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Fibroblast Activation Protein alpha/FAP

FAP (fibroblast activation protein-alpha; also known as seprase) is a type II transmembrane serine protease that degrades gelatin, Type I collagen, and N-terminal prolines. FAP is induced on reactive stromal fibroblasts in epithelial cancers, sarcomas, and granulation tissue, and may play roles in tumor invasion, tissue remodeling, and wound repair.

Alternate Names

FAP, Seprase

Gene Symbol

FAP

Additional Fibroblast Activation Protein alpha/FAP Products

Product Documents for Fibroblast Activation Protein alpha/FAP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Fibroblast Activation Protein alpha/FAP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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