Human BAFF/BLyS/TNFSF13B Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB124
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Neutralization
Cited:
Flow Cytometry, ICC, Neutralization
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 148725
Product Summary for Human BAFF/BLyS/TNFSF13B Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human BAFF
Ala134-Leu285
Accession # Q9Y275
Ala134-Leu285
Accession # Q9Y275
Specificity
Detects human BAFF in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Scientific Data Images for Human BAFF/BLyS/TNFSF13B Antibody
Cell Proliferation Induced by BAFF/BLyS/TNFSF13B and Neutralization by Human BAFF/BLyS/TNFSF13B Antibody.
Recombinant Human BAFF/BLyS/TNFSF13B (Catalog # 2149-BF) stimulates proliferation in mouse B cells in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human BAFF/BLyS/TNFSF13B (5 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human BAFF/BLyS/TNFSF13B Monoclonal Antibody (Catalog # MAB124). At 20 µg/mL, this anti-BAFF/BLyS/TNFSF13B antibody will neutralize >60% of Recombinant Human BAFF/BLyS/TNFSF13B-induced proliferation of mouse B cells.Applications for Human BAFF/BLyS/TNFSF13B Antibody
Application
Recommended Usage
Neutralization
Measured by its ability to neutralize BAFF/BLyS/TNFSF13B-induced proliferation in mouse B cells. At 20 µg/mL, this anti-BAFF/BLyS/TNFSF13B antibody will neutralize > 60% of 5 ng/mL Recombinant Human BAFF/BLyS/TNFSF13B-induced proliferation of mouse B cells.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: BAFF/BLyS/TNFSF13B
Long Name
B cell Activating Factor
Alternate Names
BLyS, CD257, TALL1, THANK, TNFSF13B, ZTNF4
Gene Symbol
TNFSF13B
UniProt
Additional BAFF/BLyS/TNFSF13B Products
Product Documents for Human BAFF/BLyS/TNFSF13B Antibody
Product Specific Notices for Human BAFF/BLyS/TNFSF13B Antibody
For research use only
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