Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all IL-1 RAcP/IL-1 R3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-1RAcP. The immunogen is located within the last 50 amino acids of IL-1RAcP. Amino Acid Squence: KWKGEKSKYPQGRFWK

Specificity

This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

66 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-1 RAcP/IL-1 R3 Antibody - BSA Free

Western Blot: IL-1 RAcP/IL-1 R3 AntibodyBSA Free [NBP1-76464]

Western Blot: IL-1 RAcP/IL-1 R3 AntibodyBSA Free [NBP1-76464]

Western Blot: IL-1 RAcP/IL-1 R3 Antibody [NBP1-76464] - Analysis of IL1RAP in HeLa whole cell lysate with anti-IL1RAP (C2) using NBP1-76464 at 1:1000 dilution.
Immunocytochemistry/ Immunofluorescence: IL-1 RAcP/IL-1 R3 Antibody - BSA Free [NBP1-76464]

Immunocytochemistry/ Immunofluorescence: IL-1 RAcP/IL-1 R3 Antibody - BSA Free [NBP1-76464]

Immunocytochemistry/Immunofluorescence: IL-1 RAcP/IL-1 R3 Antibody [NBP1-76464] - Staining of IL-1RAcP in HeLa cells with IL-1RAcP antibody at 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: IL-1 RAcP/IL-1 R3 Antibody - BSA Free [NBP1-76464]

Immunocytochemistry/ Immunofluorescence: IL-1 RAcP/IL-1 R3 Antibody - BSA Free [NBP1-76464]

Immunocytochemistry/Immunofluorescence: IL-1 RAcP/IL-1 R3 Antibody [NBP1-76464] - Staining of IL-1RAcP in HeLa cells with IL-1RAcP antibody at 5 ug/mL.

Applications for IL-1 RAcP/IL-1 R3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/Immunofluorescence

5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-1 RAcP/IL-1 R3

The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappaB inducing kinae (NIK) and of NF-kappaB, recruits to the IL-1R complex through IL-1RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.

Long Name

Interleukin 1 Receptor Accessory Protein

Alternate Names

IL-1 R3, IL-1RAcP, IL1RAcP, IL1RAP

Gene Symbol

IL1RAP

UniProt

AF029213 (Human)

Additional IL-1 RAcP/IL-1 R3 Products

Product Documents for IL-1 RAcP/IL-1 R3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-1 RAcP/IL-1 R3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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