IL-12/IL-35 p35 Antibody (2038C) [mFluor Violet 500 SE]
Novus Biologicals, part of Bio-Techne | Catalog # FAB15701MFV500
Recombinant Monoclonal Antibody.
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunocytochemistry, Intracellular Staining by Flow Cytometry
Label
mFluor Violet 500 SE
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # 2038C
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-12 p40 and human IL-12 p35
Ile23-Ser328 of p40, Arg23-Ser219 of p35
Accession # P29460 (p40) & P29459 (P35)
Ile23-Ser328 of p40, Arg23-Ser219 of p35
Accession # P29460 (p40) & P29459 (P35)
Specificity
Detects human IL-12/IL-35 p35 in direct ELISAs. Detects the IL-12/IL-35 p35 subunit either as part of the IL-12 p40/p35 heterodimer or as the IL-12/IL-35 p35 monomer. This antibody does not detect the IL-12/IL-23 p40 subunit.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Applications for IL-12/IL-35 p35 Antibody (2038C) [mFluor Violet 500 SE]
Application
Recommended Usage
Immunocytochemistry
Optimal dilutions of this antibody should be experimentally determined.
Intracellular Staining by Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
0
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: IL-12/IL-35 p35
Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.
Long Name
Interleukin 12 p35
Alternate Names
IL-12A, IL35p35
Additional IL-12/IL-35 p35 Products
Product Documents for IL-12/IL-35 p35 Antibody (2038C) [mFluor Violet 500 SE]
Product Specific Notices for IL-12/IL-35 p35 Antibody (2038C) [mFluor Violet 500 SE]
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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