Islet-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21276

Novus Biologicals, part of Bio-Techne
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NBP3-21276-25ul
NBP3-21276-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Islet-1 Antibodies »

Product Summary for Islet-1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Islet-1 Antibody

Immunocytochemistry/Immunofluorescence: Islet-1 Antibody [NBP3-21276] -

Immunocytochemistry/Immunofluorescence: Islet-1 Antibody [NBP3-21276] -

Staining of human cell line SH-SY5Y shows localization to nucleoplasm & mitochondria.

Applications for Islet-1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Islet-1

Islet 1 encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Alternate Names

ISL1, Islet1

Gene Symbol

ISL1

Additional Islet-1 Products

Product Documents for Islet-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Islet-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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