Mitofusin 2 Antibody (10F6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15201

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-15201
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 10F6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Mitofusin 2 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Mitofusin 2. UniProt ID (O95140).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Mitofusin 2 Antibody (10F6)

Immunohistochemistry: Mitofusin 2 Antibody (10F6) [NBP3-15201] - IHC image of Mitofusin 2 antibody diluted at 1:100 and staining in paraffin-embedded human kidney tissue. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 minutes at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Applications for Mitofusin 2 Antibody (10F6)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, and 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: Mitofusin 2

MFN2 encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Alternate Names

CMT2A, CMT2A2, CPRP1, HSG, MARF, MFN2

Gene Symbol

MFN2

Additional Mitofusin 2 Products

Product Documents for Mitofusin 2 Antibody (10F6)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Mitofusin 2 Antibody (10F6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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