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Mitofusin 2 Antibody (SR2236)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21710

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21710-100ul
NBP3-21710-50ul

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2236

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from human Mitofusin 2 (Uniprot #: O95140)

Specificity

Detects endogenous levels of total Mitofusin 2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Mitofusin 2 Antibody (SR2236)

Western Blot: Mitofusin 2 Antibody (SR2236) [NBP3-21710] -

Western Blot: Mitofusin 2 Antibody (SR2236) [NBP3-21710] - Western blot analysis using NBP3-21710 in (1) HeLa cell lysate; (2) Mouse kidney lysate.

Immunohistochemistry: Mitofusin 2 Antibody (SR2236) [NBP3-21710] -

Immunohistochemistry: Mitofusin 2 Antibody (SR2236) [NBP3-21710] - Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using NBP3-21710.

Immunocytochemistry/Immunofluorescence: Mitofusin 2 Antibody (SR2236) [NBP3-21710] -

Immunocytochemistry/Immunofluorescence: Mitofusin 2 Antibody (SR2236) [NBP3-21710] - Immunofluorescent analysis of Hela cells, using NBP3-21710.

Applications for Mitofusin 2 Antibody (SR2236)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mitofusin 2

MFN2 encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Alternate Names

CMT2A, CMT2A2, CPRP1, HSG, MARF, MFN2

Gene Symbol

MFN2

Additional Mitofusin 2 Products

Product Documents for Mitofusin 2 Antibody (SR2236)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mitofusin 2 Antibody (SR2236)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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