TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37724

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Block/Neutralize, CyTOF-ready, Flow Cytometry, Functional, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # H398

Format

Azide and BSA Free

Concentration

1 mg/ml

View all TNF RI/TNFRSF1A Antibodies »

Product Summary for TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free

Immunogen

Recombinant full length human CD120a.

Specificity

Antibody recognizes the extracellular domain of CD120a, a 55 kDa receptor for tumor necrosis factor. Antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free

Flow Cytometry: TNF RI/TNFRSF1A Antibody (H398) - Azide Free [NBP2-37724] - Analysis (surface staining) of CD120a in human peripheral blood with anti-human CD120a (H398) purified, GAM-APC.
TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free Flow Cytometry: TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free [NBP2-37724]

Flow Cytometry: TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free [NBP2-37724]

Surface staining pattern of human peripheral whole blood stained using anti-human CD120a (H398) purified antibody (low endotoxin, concentration in sample 3 ug/ml) GAM APC.

Applications for TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Immunohistochemistry-Frozen

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

1:10-1:500
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Endotoxin Level

Endotoxin level is less than 0.01 EU/ug of the protein

Formulation

PBS (pH 7.4), 0.2 um filter sterilized

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TNF RI/TNFRSF1A

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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