N-methylated pomalidomide

Name: N-methylated pomalidomide
Brand: Tocris Bioscience
SKU: 7716

Tocris Bioscience, part of Bio-Techne | Catalog # 7716

COA / SDS

Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control

Key Product Details

Description:	Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control
Chemical Name:	4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity:	≥95% (HPLC)
Molecular Weight:	287.27

View Full Technical Details for N-methylated pomalidomide

Technical Data
Citations

Biological Activity for N-methylated pomalidomide

N-methylated pomalidomide is a functionalized cereblon ligand for PROTAC^® research and development. Can be used to generate negative controls for Pomalidomide (Cat. No. 6302)-based Degraders. Does not bind to cereblon. Part of a range of functionalized tool molecules for PROTAC R&D. Can also be used as a Pomalidomide negative control.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Technical Data for N-methylated pomalidomide

M. Wt	287.27
Formula	C₁₄H₁₃N₃O₄
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	1352827-50-9
PubChem ID	58572149
InChi Key	YSWQOCGODHPKED-UHFFFAOYSA-N
Smiles	O=C1C=2C=CC=C(N)C2C(=O)N1C3C(=O)N(C(=O)CC3)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for N-methylated pomalidomide

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	28.73	100

Preparing Stock Solutions for N-methylated pomalidomide

The following data is based on the product molecular weight 287.27.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.48 mL	17.41 mL	34.81 mL
5 mM	0.70 mL	3.48 mL	6.96 mL
10 mM	0.35 mL	1.74 mL	3.48 mL
50 mM	0.07 mL	0.35 mL	0.70 mL

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Product Documents for N-methylated pomalidomide

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.