PM 102

Name: PM 102
Brand: Tocris Bioscience
SKU: 4034

Tocris Bioscience, part of Bio-Techne | Catalog # 4034

COA / SDS

Antagonist of heparin (Cat. No. 2812)

Discontinued Product

4034 has been discontinued. View all Cell Adhesion Inhibitors products.

Key Product Details

Description:	Antagonist of heparin (Cat. No. 2812)
Molecular Weight:	5830

View Full Technical Details for PM 102

Technical Data
Citations

Biological Activity for PM 102

PM 102 is a peptide that reverses the anticoagulant effect of heparin (Cat. No. 2812). Potently binds heparin (K_d = 36 nM in vitro).

Licensing Information

Sold under license

Technical Data for PM 102

M. Wt	5830
Formula	C₂₃₅H₄₂₅N₁₁₁O₆₄
Single Letter Sequence	AEARARRAAARAARRAKK(AEARARRAAARAARRA)PX(AEARARRAAARAARRA)EN (Modifications: Ala-1 = N-terminal Ac, Ala-19 = ε-Ac, X-36 = Dpr, Ala-37 = β-Ac, Glu-53 = C-terminal Amide)
Storage	Store at -20°C
CAS Number	1234564-95-4
PubChem ID	16130295
InChi Key	ZPNFWUPYTFPOJU-LPYSRVMUSA-N
Smiles	C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)NC(CNC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for PM 102

References are publications that support the biological activity of the product.

Shenoy Development of he. antagonists with focused biological activity. Curr.Pharmaceut.Des.
Schick Novel concatameric heparin-binding peptides reverse he. and low-molecular-weight he. anticoagulant activities in patient plasma in vitro and in rats in vivo. Blood
Cushing Reversal of heparin-induced increases in aPTT in the rat by PM102, a novel he. antagonist. Eur.J.Pharmacol. 2010 PMID: 20307530