Tobramycin

Name: Tobramycin
Brand: Tocris Bioscience
SKU: 5390
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 5390

(1)

Citations (3)

COA / SDS

Aminoglycoside antibiotic

Key Product Details

Description:	Aminoglycoside antibiotic
Chemical Name:	O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine
Molecular Weight:	467.52

View Full Technical Details for Tobramycin

Technical Data
Citations / Reviews (1)

Biological Activity for Tobramycin

Tobramycin is an aminoglycoside antibiotic. Exhibits antibacterial activity against strains of Enterobacteriaceae, Pseudomonas and Staphylococcus aureus. Shown to protect lung epithelial cells in vitro against injury from cystic fibrosis bronchial secretions and H₂O₂.

Technical Data for Tobramycin

M. Wt	467.52
Formula	C₁₈H₃₇N₅O₉
Storage	Store at +4°C
CAS Number	32986-56-4
PubChem ID	36294
InChi Key	NLVFBUXFDBBNBW-PBSUHMDJSA-N
Smiles	O[C@H]1C[C@@H](N)[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)([H])O[C@@H]1CN

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Tobramycin

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	46.75	100

Preparing Stock Solutions for Tobramycin

The following data is based on the product molecular weight 467.52.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.14 mL	10.69 mL	21.39 mL
5 mM	0.43 mL	2.14 mL	4.28 mL
10 mM	0.21 mL	1.07 mL	2.14 mL
50 mM	0.04 mL	0.21 mL	0.43 mL

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Reconstitution Calculator

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References for Tobramycin

References are publications that support the biological activity of the product.

Dienstag and Neu In vitro studies of tobramycin, an aminoglycoside antibiotic. Antimicrob.Agents Chemother. 1972 PMID: 4670427