Webinar: Methods and Reagents for Culturing and Characterizing Organoids and Cancer Spheroids

Organoids are self-organizing, three-dimensional structures derived from adult or induced pluripotent stem cells. They provide a unique physiologically relevant system as their morphology (both cell identity and organization) mimics the tissue architecture of the organ from which they are obtained. These aspects make them invaluable in vitro models for human development, disease modeling, drug discovery and cell therapy development.

However, additional technological developments are necessary to truly unleash the full potential of an organoid system. These advancements include creating suitable and reproducible culture conditions with matrices, media, and high throughput analytical assays for different organoid types. Bio-Techne has extensive experience and offers a strong and diverse portfolio for the generation, maintenance and characterization of organoids and other 3-D culture systems such as spheroids. In this presentation, we demonstrate techniques to culture and perform high-throughput analysis of multiple organoid and cancer models.

Speakers

Xi Lu, Ph. D.

Senior Scientist, Cell and Gene Therapy, Bio-Techne

Xi Lu oversees development for multiple stem cell and immune therapy products including media and matrices. Xi’s post-doctoral research works at Uppsala University and also UTH Health Science Center at Houston focused on biomaterials for tissue regeneration including bone and nerve. Xi received his Ph.D. in Biomedical Engineering from Washington University in St Louis where he developed microfluidic devices for investigating axonal degeneration. He holds a B.S. in Biomedical engineering from Georgia Tech.

Tahmina Naqvi

Senior Research Associate, Cell and Gene Therapy, Bio-Techne

Tahmina Naqvi is responsible for the development of organoid workflow solutions. Prior to joining Bio-Techne she worked as a Research Scientist at University of Minnesota, ISurTec, LLC, Surmodics, Inc and Prolexys Pharmaceuticals in Utah. She has been a project leader for numerous projects including synthetic matrices for mammalian cells, ECIS and microfluidic devices, high throughput drug screening assays, biomaterials for bone tissue regeneration and human stem cell differentiation pathways. She holds a MS in Biology from University of Karachi, Pakistan.