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Key Product Details

Species Reactivity

Validated:

Human

Applications

Block/Neutralize, Immunocytochemistry/ Immunofluorescence

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Rabbit IgG Kappa Clone # chi220

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for CD40 Ligand/TNFSF5 Antibody (chi220) [FITC]

Immunogen

This antibody was generated by immunizing female BALB/c mice with a fusion protein containing extracellular domain of human CD40 Ligand/TNFSF5 fused to the hinge CH2 and CH3 domains of a murine IgG2b antibody.

Specificity

This antibody binds the CD40 Ligand/TNFSF5 and blocks the humoral immune responses to T cell dependent antigens in a dose dependent manner.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for CD40 Ligand/TNFSF5 Antibody (chi220) [FITC]

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD40 Ligand/TNFSF5

CD40L is the ligand for CD40, a member of the tumor necrosis factor (TNF) receptor superfamily. CD40L is expressed mainly on activated CD4+ T-lymphocytes as a single-pass type II membrane protein. Proteolytic processing of the membrane form results in a soluble secreted form of CD40L.

Alternate Names

CD154, CD40L, CD40LG, gp39, TNFSF5, TRAP

Gene Symbol

CD40LG

Additional CD40 Ligand/TNFSF5 Products

Product Documents for CD40 Ligand/TNFSF5 Antibody (chi220) [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD40 Ligand/TNFSF5 Antibody (chi220) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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