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CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-75907

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Block/Neutralize, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Human IgG1 kappa Clone # hu5c8 (Ruplizumab)

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Summary for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Immunogen

Human CD40L

Specificity

The antibody binds to CD40L with an IC50 of 0.845 ug/ml.

Clonality

Monoclonal

Host

Human

Isotype

IgG1 kappa

Scientific Data Images for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Western Blot: CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) [NBP2-75907] - Rat spleen (lane 1), rat muscle (lane 2), rat bladder (lane 3), human breast tumour (lane 4) and human thyroid tumour (lane 5) samples were resolved on a 10% SDS PAGE gel and blots probed with NBP2-75907 at 1 ug/ml before being detected by a secondary antibody. The expected band size (29 kDa) is seen in the human-derived samples, as well as bands corresponding to dimers and other multimers.

Applications for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: CD40 Ligand/TNFSF5

CD40L is the ligand for CD40, a member of the tumor necrosis factor (TNF) receptor superfamily. CD40L is expressed mainly on activated CD4+ T-lymphocytes as a single-pass type II membrane protein. Proteolytic processing of the membrane form results in a soluble secreted form of CD40L.

Alternate Names

CD154, CD40L, CD40LG, gp39, TNFSF5, TRAP

Gene Symbol

CD40LG

Additional CD40 Ligand/TNFSF5 Products

Product Documents for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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