Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Human IgG1 kappa Clone # hu5c8 (Ruplizumab)

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CD40 Ligand/TNFSF5 Antibodies »

Product Summary for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) [DyLight 488]

Immunogen

Human CD40L

Specificity

The antibody binds to CD40L with an IC50 of 0.845 ug/ml.

Clonality

Monoclonal

Host

Human

Isotype

IgG1 kappa

Applications for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) [DyLight 488]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD40 Ligand/TNFSF5

CD40L is the ligand for CD40, a member of the tumor necrosis factor (TNF) receptor superfamily. CD40L is expressed mainly on activated CD4+ T-lymphocytes as a single-pass type II membrane protein. Proteolytic processing of the membrane form results in a soluble secreted form of CD40L.

Alternate Names

CD154, CD40L, CD40LG, gp39, TNFSF5, TRAP

Gene Symbol

CD40LG

Additional CD40 Ligand/TNFSF5 Products

Product Documents for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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