Cordycepin

Name: Cordycepin
Brand: Tocris Bioscience
SKU: 2294
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2294

(1)

Citations (3)

COA / SDS

RNA synthesis inhibitor

Key Product Details

Description:	RNA synthesis inhibitor
Chemical Name:	3'-Deoxyadenosine
Purity:	≥98% (HPLC)
Molecular Weight:	251.24

View Full Technical Details for Cordycepin

Technical Data
Citations / Reviews (1)

Biological Activity for Cordycepin

Cordycepin is a nucleoside analog that acts as an anticancer and antifungal agent. Can be converted to 3'-deoxyadenosine triphosphate (3'-dATP), which inhibits ATP-dependent DNA synthesis. Inhibits growth of various tumor cells in vitro.

Technical Data for Cordycepin

M. Wt	251.24
Formula	C₁₀H₁₃N₅O₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	73-03-0
PubChem ID	6303
InChi Key	OFEZSBMBBKLLBJ-BAJZRUMYSA-N
Smiles	NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](CO)C[C@H]3O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Cordycepin

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	25.12	100

Preparing Stock Solutions for Cordycepin

The following data is based on the product molecular weight 251.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.98 mL	19.90 mL	39.80 mL
5 mM	0.80 mL	3.98 mL	7.96 mL
10 mM	0.40 mL	1.99 mL	3.98 mL
50 mM	0.08 mL	0.40 mL	0.80 mL

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Reconstitution Calculator

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References for Cordycepin

References are publications that support the biological activity of the product.

Sugar and McCaffrey Antifungal activity of 3'-deoxyadenosine (cordycepin). Antimicrob.Agents Chemother. 1998 PMID: 9624488
Kodama Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT⁺) leukemic cells. Biochem.Pharmacol. 2000 PMID: 10609556
Gumport and Edelhei The synthesis of 3'-dATP and its use as an inhibitor of ATP-dependent DNA synthesis in toluene-treated Escherichia coli. Biochemistry 1976 PMID: 779831