B7-2/CD86: Proteins and Enzymes
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
13 results for "B7-2/CD86 Proteins and Enzymes" in Products
13 results for "B7-2/CD86 Proteins and Enzymes" in Products
B7-2/CD86: Proteins and Enzymes
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
Source: | NS0 |
Accession #: | AAB03814 |
Applications: | BA |
Fc Chimera
Source: | CHO |
Accession #: | AAB03814.1 |
Applications: | BA |
Source: | HEK293 |
Accession #: | XP_005548057 |
Applications: | BA |
Source: | HEK293 |
Accession #: | NP_787058.4 |
Applications: | BA |
Fc Chimera
Source: | HEK293 |
Accession #: | XP_005548057 |
Applications: | BA |
Biotinylated
Source: | CHO |
Accession #: | AAH40261.1 |
Applications: | BA, BA |
Fc Chimera
Source: | CHO |
Accession #: | AAB03814.1 |
Applications: | BA |
Source: | NS0 |
Accession #: | O35531 |
Applications: | BA |
Source: | Sf 21 (baculovirus) |
Accession #: | Q549Q9 |
Applications: | BA |
Source: | CHO |
Accession #: | AAB03814.1 |
Applications: | BA |
Source: | HEK293 |
Accession #: | NP_787058 |
Applications: | BA |
Applications: | PAGE |