CXCR4 Products
CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis.
363 results for "CXCR4" in Products
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CXCR4 Products
CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis.
363 results for "CXCR4" in Products
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #44716 |
Applications: | Flow, IHC, CyTOF-ready, Neut |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #247506 |
Applications: | Flow, IHC, CyTOF-ready, ICC, Neut |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5 |
Applications: | Flow, CyTOF-reported, Neut |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5 |
Applications: | Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA, Flow |
Reactivity: | Human, Mouse, Rat, Sheep |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, Func, KD |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #44717 |
Applications: | Flow, CyTOF-ready, Neut |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #44708 |
Applications: | Neut |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA, Flow, +2 More |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #44717 |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #247506 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5 |
Applications: | Flow |
Reactivity: | Human, Mouse, Rat, Monkey, Primate, +3 More |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #247506R |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #247506R |
Applications: | Flow, IHC, CyTOF-ready, ICC |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #44717 |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5R |
Applications: | Flow, Neut |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5R |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5 |
Applications: | Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA, KD |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #44717 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #247506R |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #12G5 |
Applications: | Flow |