GM-CSF: Proteins and Enzymes
GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the inflammatory activation of dendritic cells, microglia, alveolar macrophages, and eosinophils. In addition, it cooperates with G-CSF in promoting tumor cell proliferation and invasion. GM-CSF signals through a receptor complex composed of GM-CSF R alpha and the Common beta Chain (beta c) with Syndecan-2 as a potential co-receptor. The beta c subunit is shared by the receptor complexes for IL-3 and IL-5.
A New and Improved Recombinant Human GM-CSF is Now Available!
Our new Recombinant Human GM-CSF protein (Catalog # 7954-GM) has lower endotoxin specifications than 215-GM and is CHO-expressed. The same R&D Systems quality at a more economical price. Receive 25% off your first order of Recombinant Human GM-CSF Protein, 7954-GM when you purchase today!
20 results for "GM-CSF Proteins and Enzymes" in Products
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GM-CSF: Proteins and Enzymes
GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the inflammatory activation of dendritic cells, microglia, alveolar macrophages, and eosinophils. In addition, it cooperates with G-CSF in promoting tumor cell proliferation and invasion. GM-CSF signals through a receptor complex composed of GM-CSF R alpha and the Common beta Chain (beta c) with Syndecan-2 as a potential co-receptor. The beta c subunit is shared by the receptor complexes for IL-3 and IL-5.
A New and Improved Recombinant Human GM-CSF is Now Available!
Our new Recombinant Human GM-CSF protein (Catalog # 7954-GM) has lower endotoxin specifications than 215-GM and is CHO-expressed. The same R&D Systems quality at a more economical price. Receive 25% off your first order of Recombinant Human GM-CSF Protein, 7954-GM when you purchase today!
20 results for "GM-CSF Proteins and Enzymes" in Products
Analyzed by SEC-MALS
| Source: | CHO |
| Accession #: | P04141 |
| Applications: | BA |
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | Q14AD9 |
| Applications: | BA |
Animal-Free.
| Source: | E. coli |
| Accession #: | P04141.1 |
| Applications: | BA |
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | P04141.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q29118 |
| Applications: | BA |
Intended for preclinical researchers who may transition to GMP GM-CSF for their clinical work
| Source: | E. coli |
| Accession #: | P04141.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P48750.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P48749.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | AAC06041 |
| Applications: | BA |
| Applications: | Bioactivity, PAGE |
| Applications: | Bioactivity, PAGE |
| Applications: | Bioactivity |
| Applications: | Bioactivity |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |