IL-1 beta/IL-1F2: Proteins and Enzymes
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
22 results for "IL-1 beta/IL-1F2 Proteins and Enzymes" in Products
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IL-1 beta/IL-1F2: Proteins and Enzymes
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
22 results for "IL-1 beta/IL-1F2 Proteins and Enzymes" in Products
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | NP_000567 |
| Applications: | BA |
Animal-Free.
| Source: | E. coli |
| Accession #: | NP_000567.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_032387 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q63264 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_001075670 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P26889.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q28386 |
| Applications: | BA |
Intended for preclinical researchers who may transition to GMP IL-1beta for their clinical work
| Source: | E. coli |
| Accession #: | NP_000567.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_001033060 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P41687.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | AAL18817 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P48090 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q9WVG1.1 |
| Applications: | BA |
| Applications: | AC |
| Applications: | ELISA, Func |
| Applications: | Func |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |
| Applications: | PAGE, Bioactivity |
