Multidrug Transporter Inhibitors: Small Molecules and Peptides
13 results for "Multidrug Transporter Inhibitors Small Molecules and Peptides" in Products
13 results for "Multidrug Transporter Inhibitors Small Molecules and Peptides" in Products
Multidrug Transporter Inhibitors: Small Molecules and Peptides
Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor
| Chemical Name: | 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine |
| Purity: | ≥99% (HPLC) |
MRP and OAT3 inhibitor
| Chemical Name: | 4-(Dipropylsulfamoyl)benzoic acid |
| Purity: | ≥98% (HPLC) |
Inhibitor of BCRP-mediated multidrug resistance
| Chemical Name: | (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione |
| Purity: | ≥98% (HPLC) |
Potent and selective BCRP inhibitor
| Chemical Name: | (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester |
| Purity: | ≥99% (HPLC) |
High affinity P-gp inhibitor
| Alternate Names: | LY 335979 |
| Chemical Name: | (αR)-4-[(1aα,6α,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-1-piperazineethanol trihydrochloride |
| Purity: | ≥97% (HPLC) |
Selective MRP1 and P-gp inhibitor
| Chemical Name: | N-[3-(4-Morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide |
| Purity: | ≥95% (HPLC) |
Selective BCRP inhibitor
| Chemical Name: | N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide |
| Purity: | ≥98% (HPLC) |
P-gp and BCRP inhibitor
| Alternate Names: | GF 120918 |
| Chemical Name: | N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Inhibitor of P-gp-mediated MDR
| Alternate Names: | Valspodar |
| Chemical Name: | 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A |
| Purity: | ≥98% (HPLC) |
Selective MRP4 inhibitor
| Chemical Name: | 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione |
| Purity: | ≥98% (HPLC) |
P-gp inhibitor
| Chemical Name: | 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-2[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent P-glycoprotein (P-gp) inhibitor
| Chemical Name: | N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent CysLT1 (LTD4) inverse agonist. Also MRP1 inhibitor
| Alternate Names: | L-660711 |
| Chemical Name: | 3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid |
