Osteoprotegerin/TNFRSF11B: Proteins and Enzymes
Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.
6 results for "Osteoprotegerin/TNFRSF11B Proteins and Enzymes" in Products
6 results for "Osteoprotegerin/TNFRSF11B Proteins and Enzymes" in Products
Osteoprotegerin/TNFRSF11B: Proteins and Enzymes
Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.
| Source: | NS0 |
| Accession #: | Q6PI12 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | AAB53709 |
| Applications: | BA |
| Applications: | PAGE |
| Source: | NS0 |
| Accession #: | AAB53709.1 |
| Applications: | BA |
| Applications: | Bioactivity, PAGE |
| Applications: | Bioactivity |