ARF GTPase Inhibitors: Small Molecules and Peptides
Arf GTPases regulate vesicle trafficking, budding and tethering, and cytoskeleton organization. It is a family that includes Class I, II and III Arfs, and related GTPases. Aberrant activity and expression of specific family members has been linked to cancer progression and tumor invasion and proliferation.
4 results for "ARF GTPase Inhibitors Small Molecules and Peptides" in Products
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ARF GTPase Inhibitors: Small Molecules and Peptides
Arf GTPases regulate vesicle trafficking, budding and tethering, and cytoskeleton organization. It is a family that includes Class I, II and III Arfs, and related GTPases. Aberrant activity and expression of specific family members has been linked to cancer progression and tumor invasion and proliferation.
4 results for "ARF GTPase Inhibitors Small Molecules and Peptides" in Products
Selective ARF6 inhibitor
| Chemical Name: | 3-(4-Chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one |
| Purity: | ≥98% (HPLC) |
Potent, selective and reversible inhibitor of GBF1 ArfGEF
| Chemical Name: | 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline |
| Purity: | ≥98% (HPLC) |
ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling
| Chemical Name: | (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol |
| Purity: | ≥98% (HPLC) |
Sec7-specific GEF inhibitor; selective for cytohesin family
| Chemical Name: | N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide |
| Purity: | ≥98% (HPLC) |
