ABCB5 Antibody [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77687V

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-77687AF350

Alexa Fluor 405

NBP1-77687AF405

Alexa Fluor 488

NBP1-77687AF488

Alexa Fluor 532

NBP1-77687AF532

Alexa Fluor 594

NBP1-77687AF594

Alexa Fluor 647

NBP1-77687AF647

Alexa Fluor 700

NBP1-77687AF700

Alexa Fluor 750

NBP1-77687AF750

Allophycocyanin

NBP1-77687APC

Biotin

NBP1-77687B

DyLight 350

NBP1-77687UV

DyLight 488

NBP1-77687G

DyLight 550

NBP1-77687R

DyLight 594

NBP1-77687DL594

DyLight 650

NBP1-77687C

DyLight 680

NBP1-77687FR

DyLight 755

NBP1-77687IR

FITC

NBP1-77687F

HRP

NBP1-77687H

Janelia Fluor 549

NBP1-77687JF549

Janelia Fluor 646

NBP1-77687JF646

mFluor Violet 450 SE

NBP1-77687MFV450

mFluor Violet 500 SE

NBP1-77687MFV500

mFluor Violet 610 SE

NBP1-77687MFV610

PE

NBP1-77687PE

PerCP

NBP1-77687PCP

Forumulation

Catalog #

BSA Free

NBP1-77687

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ABCB5 Antibodies »

Product Summary for ABCB5 Antibody [DyLight 405]

Immunogen

A synthetic peptide made to an internal portion of the human ABCB5 protein (between residues 150-200) [UniProt Q2M3G0]

Localization

Cell membrane; Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for ABCB5 Antibody [DyLight 405]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ABCB5

The ATP-binding cassette sub-family B member 5 (ABCB5) is an ABC transporter and PGP member. It is highly expressed in skin and in malignant melanoma. When two abnormal growths of tissues occur, resulting in multiple malignancies, ABCB5 is often highly expressed. This elevated expression in tumor cells can indicate a propensity towards therapeutic failure in many cases. Analysis of ABCB5 concentrations in tumors has been suggested as a fairly dependable qualitative biomarker for assessing the malignancy of melanomas.

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 5

Alternate Names

ABCB5 P-gp, ABCB5alpha, ABCB5beta, ATP-binding cassette protein, ATP-binding cassette sub-family B member 5, ATP-binding cassette, sub-family B (MDR/TAP), member 5, EC 3.6.3, EC 3.6.3.44, EST422562, P-glycoprotein ABCB5

Gene Symbol

ABCB5

Additional ABCB5 Products

Product Documents for ABCB5 Antibody [DyLight 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for ABCB5 Antibody [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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