Interrogating the Brain's Clock: How Spatial Genomics Enhances SCN Research
RNAscope spatial analysis greatly improves our research by offering high-resolution visualization of gene expression within the SCN...
Testimonials and Interviews from your Peers
Read testimonials and interviews from your peers, to find out how scientists like you are driving pioneering research and diagnostics forward using Bio-Techne reagents, kits and instruments.
Our testimonials cover a range of research areas and applications, using everything from gold standard to GMP reagents, and revolutionary, award-winning instruments.
Simply filter in the left-hand menu and see what your peers have to say.
Molecular Mysteries of the Rodent Brain: A Researcher’s Spatial Journey
My single-cell transcriptomic experiments have focused on uncovering and understanding the molecular makeup of cellular heterogeneity in the rodent brain.
Implement – and Walk Away: Automating RNA ISH to build a robust, accurate picture of molecular pathways
By introducing the automated method, we have improved workflow productivity and produced clear staining in a standardized and repeatable way.
Insights on Dual ISH-IHC: Guidance from the experts on performing RNAscope™ ISH and immunohistochemistry on the same sample
RNAscope™ Spotlights
What our customers are saying:
Unlocking the power of organoids in personalized medicine
It is key technologies like RNAscope used after scRNAseq that is enabling us to visualize the genes in the context of the whole tissue...and pave the way for therapeutic approaches to intestinal diseases.
Harnessing spatial biology to uncover the cellular landscape of colorectal cancer
Being able to spatially resolve cells in tissue using tools like RNAscope™ …will have a lot of clinical relevance in the future… that’s where the real power of this can be seen going from bench to bedside.
Shedding Light on Human Cerebral Cortical Folding and Channelopathies
The RNAscope assay was very helpful in discovering this, not only because we were able to confidently discern between the different sodium channels, but also because we could use the RNAscope Multiplex Fluorescent kit v2 in situ assay to co-localize gene expression with cell types.
Insights into viral pathogenesis: Determination of causation by highly sensitive and specific viral RNA detection and localization with RNAscope ISH
With its importance in understanding causality and the viral-host relationship, RNAscope technology has been a vital tool in my research... a method as sensitive as RNAscope assay with spatial resolution is absolutely irreplaceable for our confidence in determining viral contribution to a disease.
Detecting a Novel Circovirus in Foxes with Meningoencephalitis: How custom RNAscope™ assay probes are enhancing viral understanding
In fact, we would certainly recommend RNAscope technology to researchers wanting to examine a target of interest for which there is not a reliable antibody available
Exploring GPCR expression in the eye: From discovery with NGS to spatial and quantitative expression confirmation with RNAscope™ technology
Because RNAscope can detect expression of multiple genes in parallel, it can tell us whether those genes discovered through RT-PCR are co-expressed in the same cell or not – information that is very valuable and hard to obtain by other means.
Development of Prostate Cancer Personalized Medicine: Advancing analysis of prostate tumor molecular heterogeneity by combined immunohistochemistry and novel RNA in situ hybridization
The development of combined protein and RNA detection methods may alleviate many concerns for accurate detection of biomarkers, and I can see this being the standard practice in future molecular cancer profiling... Given the unique probe design and detection chemistry of the RNAscope method, we were able to get results with high specificity and sensitivity for many probes that we have used in my laboratory. To date we don’t have any comparable technology for the reliable detection of RNA in FFPE tissues other than RNAscope.