Oligomycin A

Name: Oligomycin A
Brand: Tocris Bioscience
SKU: 4110
Rating: 4 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4110

(1)

Citations (24)

COA / SDS

Inhibitor of mitochondrial ATPase

Key Product Details

Description:	Inhibitor of mitochondrial ATPase
Chemical Name:	(1R,4E,5'S,6S,6'S,7R,8S,10R,11R, 12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione
Purity:	≥98% (HPLC)
Molecular Weight:	791.06

View Full Technical Details for Oligomycin A

Technical Data
Citations / Reviews (1)

Biological Activity for Oligomycin A

Oligomycin A is an inhibitor of mitochondrial ATP synthase and uncoupler of oxidative phosphorylation. Antibiotic; exhibits anti-tumor activity.

Technical Data for Oligomycin A

M. Wt	791.06
Formula	C₄₅H₇₄O₁₁
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	579-13-5
PubChem ID	5281899
InChi Key	MNULEGDCPYONBU-WMBHJXFZSA-N
Smiles	CC[C@](CC[C@@]([H])(O[C@@]2(CC[C@@H](C)[C@@]([H])(C[C@@H](O)C)O2)[C@@H]1C)[C@H](C)[C@]1([H])OC(/C=C/[C@H]([C@@H]([C@@H](C)C([C@@H](C)[C@H](O)[C@H]3C)=O)O)C)=O)([H])/C=C/C=C/C[C@H](C)[C@@H](O)[C@](C)(O)C3=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Oligomycin A

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	ethanol	7.91	10

Preparing Stock Solutions for Oligomycin A

The following data is based on the product molecular weight 791.06.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.64 mL	63.21 mL	126.41 mL
0.5 mM	2.53 mL	12.64 mL	25.28 mL
1 mM	1.26 mL	6.32 mL	12.64 mL
5 mM	0.25 mL	1.26 mL	2.53 mL

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References for Oligomycin A

References are publications that support the biological activity of the product.

Salomon Apoptolidin, a selective cytotoxic agent, is an inhibitor of F₀F₁-ATPase. Chem.Biol. 2001 PMID: 11182320