Webinar: 5th Virtual Bio-Techne Targeted Protein Degradation and Induced Proximity Symposium

The 5th Virtual Bio-Techne Targeted Protein Degradation and Induced Proximity Symposium covers new developments from the leading scientists working in induced proximity research.

We have an exclusive first public presentation of new work from the Gray Lab at Stanford, plus new data of a novel mechanism of action from Amphista. Topics covered include: transcriptional kinases to activate apoptosis, degradation of BRD9 by a novel “targeted glue”, discovery of protein degraders and stabilizers, mechanisms of degrader-targeted protein ubiquitinability, and degraders of HIV-1 Nef for antiretroviral drug development.

Moderator: Joel Cresser-Brown (Bio-Techne)

Unbiased Discovery of Protein Degraders and Stabilizers with Proteome-Scale Induced Proximity Screens
Juline Poirson (Taipale Lab)
University of Toronto

Mechanism of Degrader-Targeted Protein Ubiquitinability
Charlotte Crowe (Ciulli Lab)
University of Dundee

Targeted Degraders of HIV-1 Nef as a New Approach to Antiretroviral Drug Development
Tom Smithgall
University of Pittsburgh School of Medicine

HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development
Breanna Zerfas
Dana Farber Cancer Institute

Borrowing Transcriptional Kinases To Activate Apoptosis
Basel Karim (Gray Lab)
Stanford University

Degradation of BRD9 by a Novel “Targeted Glue”
Scott Hughes
Amphista Therapeutics