beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
446 results for "beta-Catenin" in Products
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beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
446 results for "beta-Catenin" in Products
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
| Reactivity: | Human, Mouse, Rat, Primate, Chicken, +1 More |
| Details: | Mouse IgG1 Monoclonal Clone #12F7 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
Potent tankyrase inhibitor
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ChIP, CyTOF-ready, +2 More |
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% (HPLC) |
Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma
| Chemical Name: | 4-[3-Fluoro-4-[[[[4-(1,1,2,2,2-pentafluoroethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #196621 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat, Canine, Rabbit, +2 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +2 More |
| Assay Range: | 312 - 20,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG3 Monoclonal Clone #196618 |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #196624 |
| Applications: | WB, CyTOF-ready, ICFlow |
Wnt/β-catenin signaling inhibitor
| Chemical Name: | (5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt |
| Purity: | ≥98% (HPLC) |
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
| Reactivity: | Human, Mouse, Rat, Fish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Potent inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #9L6X0 |
| Applications: | IHC, WB, ICC/IF, IP, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #196624 |
| Applications: | ICFlow |
Inhibits TCF/β-catenin-mediated transcription
| Chemical Name: | (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CTNNB1/1509 |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTNNB1/2030R |
| Applications: | IHC, WB, ICC/IF, Flow, MA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #196624 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #196624 |
| Applications: | ICFlow |
Inhibits β-catenin-responsive transcription (CRT)
| Chemical Name: | 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedion |
| Purity: | ≥98% (HPLC) |
Wnt signaling inhibitor; inhibits β-catenin-transcription factor interactions
| Purity: | ≥95% (HPLC) |
