Thalidomide 4'-ether-alkylC8-acid

Name: Thalidomide 4'-ether-alkylC8-acid
Brand: Tocris Bioscience
SKU: 7335

Tocris Bioscience, part of Bio-Techne | Catalog # 7335

COA / SDS

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Key Product Details

Description:	Cereblon ligand with alkyl linker and terminal acid for onward chemistry
Chemical Name:	9-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]nonanoic acid
Purity:	≥95% (HPLC)
Molecular Weight:	430.46

View Full Technical Details for Thalidomide 4'-ether-alkylC8-acid

Technical Data
Citations

Biological Activity for Thalidomide 4'-ether-alkylC8-acid

Thalidomide 4'-ether-alkylC8-acid is a functionalized cereblon ligand for PROTAC^® research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with a terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for Thalidomide 4'-ether-alkylC8-acid

M. Wt	430.46
Formula	C₂₂H₂₆N₂O₇
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2225148-51-4
PubChem ID	139433330
InChi Key	JDVPWEYIVOQCDX-UHFFFAOYSA-N
Smiles	OC(CCCCCCCCOC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product Documents for Thalidomide 4'-ether-alkylC8-acid

COA

Certificate of Analysis

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