Degrader Building Blocks: Small Molecules and Peptides
159 results for "Degrader Building Blocks Small Molecules and Peptides" in Products
Search
Product Action
Conjugates
Low Endotoxin
Sample Size
Reviews
Brand
Degrader Building Blocks: Small Molecules and Peptides
159 results for "Degrader Building Blocks Small Molecules and Peptides" in Products
UBE2D degrader building block
| Chemical Name: | N-[[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-5-isoxazolyl]methyl]-2-propenamide |
| Purity: | ≥95% (HPLC) |
Functionalized VHL building block for copper-free click chemistry
| Chemical Name: | ((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl ((S)-14-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-15,15-dimethyl-12-oxo-3,6,9-trioxa-13-azahexadecyl)carbamate |
| Purity: | ≥90% (HPLC) |
VHL ligand with alkyl linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C2-COOH |
| Chemical Name: | 4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid |
| Purity: | ≥95% (HPLC) |
Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry
| Chemical Name: | 36-[[2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-21,21-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-19,26,32-trioxo-4,7,10,13,16,23-hexaoxa-20,27,31-triazahexatriacontanoic acid |
| Purity: | ≥90% (HPLC) |
Cereblon ligand with PEG linker and terminal amine for onward chemistry
| Chemical Name: | 4-[[2-(2-Aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
| Purity: | ≥95% (HPLC) |
Functionalized VHL ligand for PROTAC® development
| Chemical Name: | (2S,4R)-1-((R)-2-Acetamido-3-mercapto-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥95% (HPLC) |
Asialoglycoprotein receptor ligand with alkylC5 linker and amine group for onward chemistry
| Chemical Name: | N-[2-[[1-[2-[2-[2-[2-[[2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]-1,1-bis[[[1-[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]methyl]ethyl]-6-aminohexanamide |
| Purity: | ≥90% (HPLC) |
Cereblon ligand with PEG linker and terminal alkyne for onward chemistry
| Alternate Names: | Thalidomide - linker 5 |
| Chemical Name: | 2-(2,6-Dioxo-3-piperidinyl)-4-[2-[2-(2-propyn-1-yloxy)oxy]ethoxy]-1H-isoindole-1,3(2H)dione |
| Purity: | ≥95% (HPLC) |
Cereblon ligand with PEG linker and terminal azide for onward chemistry
| Chemical Name: | 4-[[2-(2-Azidoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
| Purity: | ≥95% (HPLC) |
Biotinylated ASGPR ligand for LYTAC research and development
| Purity: | ≥90% (HPLC) |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
| Chemical Name: | 9-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]nonanoic acid |
| Purity: | ≥95% (HPLC) |
Cereblon ligand with terminal piperidine for onward chemistry
| Chemical Name: | 3-[1,3-Dihydro-1-oxo-5-[4-(4-piperidinylmethyl)-1-piperazinyl]-2H-isoindol-2-yl]-2,6-piperidinedione dihydrochloride |
| Purity: | ≥94% (HPLC) |
Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry
| Chemical Name: | 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 2-(acetylamino)-2-deoxy-β-D-galactopyranoside |
| Purity: | ≥95% (HPLC) |
Cereblon ligand with PEG linker and terminal amine for onward chemistry
| Chemical Name: | 4-[[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
| Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
| Chemical Name: | 4-[(7-Aminoheptyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
| Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
| Chemical Name: | 4-[(5-Azidopentyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
| Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
| Chemical Name: | 5-[(8-Aminooctyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
| Purity: | ≥95% (HPLC) |
Cereblon ligand with terminal piperazine for onward chemistry
| Chemical Name: | 2-(2,6-Dioxo-3-piperidinyl)-5-(1-piperazinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C8-COOH |
| Chemical Name: | 10-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-10-oxodecanoic acid |
| Purity: | ≥95% (HPLC) |
Cereblon ligand with PEG linker and terminal acid for onward chemistry
| Alternate Names: | Pomalidomide - linker 2 |
| Chemical Name: | 3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid |
| Purity: | ≥95% (HPLC) |
Functionalized L3MBTL3 ligand for PROTACs
| Chemical Name: | 4-[[2,5-Bis[[4-(1-pyrrolidinyl)-1-piperidinyl]carbonyl]phenyl]amino]benzoic acid ditrifluoroacetate |
| Purity: | ≥95% (HPLC) |
Functionalized VHL ligand for PROTACs
| Chemical Name: | (4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Functionalized cereblon ligand for PROTAC development
| Chemical Name: | 2-(4-(2,6-Dioxopiperidin-3-yl)phenoxy)acetic acid |
| Purity: | ≥95% (HPLC) |
IAP ligand with alkyl linker and terminal amine for onward chemistry
| Chemical Name: | tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-(5-Aminopentanamido)-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-phenol-C4-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-(4-aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
