CD47 Products
CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a ubiquitous transmembrane protein that binds to SIRP family members on macrophages, neutrophils, and T cells. These interactions prevent macrophage-mediated clearance of healthy CD47-expressing cells and promote immune cell transmigration across the vascular endothelium. CD47 associates in cis with Fas on T cells and enhances Fas-mediated apoptosis; its ligation promotes T cell anergy and dampens Th1 immune responses. CD47 also associates in cis with several Integrins which can positively or negatively modulate Integrin-mediated function. CD47 binding by Thrombospondin-1 inhibits the angiogenic and vasorelaxant effects of nitric oxide. On dendritic cells and myeloma cells, CD47 ligation by TSP-1 induces giant cell formation and osteoclast differentiation.
269 results for "CD47" in Products
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CD47 Products
CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a ubiquitous transmembrane protein that binds to SIRP family members on macrophages, neutrophils, and T cells. These interactions prevent macrophage-mediated clearance of healthy CD47-expressing cells and promote immune cell transmigration across the vascular endothelium. CD47 associates in cis with Fas on T cells and enhances Fas-mediated apoptosis; its ligation promotes T cell anergy and dampens Th1 immune responses. CD47 also associates in cis with several Integrins which can positively or negatively modulate Integrin-mediated function. CD47 binding by Thrombospondin-1 inhibits the angiogenic and vasorelaxant effects of nitric oxide. On dendritic cells and myeloma cells, CD47 ligation by TSP-1 induces giant cell formation and osteoclast differentiation.
269 results for "CD47" in Products
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
Applications: | IHC, ICC/IF, ELISA, Flow, MA |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CD47/6362R |
Applications: | IHC, ELISA |
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 Monoclonal Clone #B6H12.2 |
Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB, Flow, IHC, CyTOF-ready, KO, +1 More |
Reactivity: | Mouse, Rat |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Source: | NS0 |
Accession #: | Q08722 |
Applications: | BA, BA |
Reactivity: | Mouse |
Details: | Rat IgG1 Monoclonal Clone #974222 |
Applications: | Flow, Block, CyTOF-ready |
Reactivity: | Mouse |
Details: | Rat IgG1 Monoclonal Clone #974222 |
Applications: | Flow |
Source: | NS0 |
Accession #: | Q08722 |
Applications: | BA |
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 Kappa/IgG1 Kappa Monoclonal Clone #IAP/964 + B6H12.2 |
Applications: | IHC, WB, ICC/IF, Flow |
Source: | CHO |
Accession #: | Q08722 |
Applications: | BA |
Assay Range: | 125 - 8,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #472603 |
Applications: | Flow, Block, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #CL6913 |
Applications: | IHC |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #472603 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #472603 |
Applications: | Flow |
Recombinant Monoclonal
Reactivity: | Human |
Details: | Rabbit Monoclonal Clone #BLR131H |
Applications: | IHC, WB, ICC/IF, Simple Western |
Source: | NS0 |
Accession #: | NP_034711 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #472603 |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Rat IgG1 Monoclonal Clone #974214 |
Applications: | Flow, CyTOF-ready |
Source: | NS0 |
Accession #: | Q08722.1 |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, IHC |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #472603 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #472603 |
Applications: | Flow |