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IL-8/CXCL8: Proteins and Enzymes

Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.

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17 results for "IL-8/CXCL8 Proteins and Enzymes" in Products

IL-8/CXCL8: Proteins and Enzymes

Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.

Products:

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17 results for "IL-8/CXCL8 Proteins and Enzymes" in Products

Applications: BA
Applications: BA, BA
Applications: BA
Applications: BA
Applications: BA
Applications: BA
Applications: WB, ELISA
Catalog #: NBP2-62466
Applications: WB, ELISA
Catalog #: NBP2-76183
Applications: PAGE
Catalog #: NBP2-62465
Applications: Bioactivity
Applications: AC
Applications: PAGE, Bioactivity
Applications: PAGE, Bioactivity
Applications: PAGE, Bioactivity
Applications: PAGE, Bioactivity
Applications: PAGE, Bioactivity
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