beta-Catenin: Small Molecules and Peptides
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
17 results for "beta-Catenin Small Molecules and Peptides" in Products
Search
Product Action
Conjugates
Low Endotoxin
Sample Size
Reviews
Brand
beta-Catenin: Small Molecules and Peptides
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
17 results for "beta-Catenin Small Molecules and Peptides" in Products
Potent tankyrase inhibitor
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% (HPLC) |
Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma
| Chemical Name: | 4-[3-Fluoro-4-[[[[4-(1,1,2,2,2-pentafluoroethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Wnt/β-catenin signaling inhibitor
| Chemical Name: | (5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt |
| Purity: | ≥98% (HPLC) |
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
Potent inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Purity: | ≥98% (HPLC) |
Inhibits TCF/β-catenin-mediated transcription
| Chemical Name: | (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide |
| Purity: | ≥98% (HPLC) |
Inhibits β-catenin-responsive transcription (CRT)
| Chemical Name: | 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedion |
| Purity: | ≥98% (HPLC) |
Wnt signaling inhibitor; inhibits β-catenin-transcription factor interactions
| Purity: | ≥95% (HPLC) |
Inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-[4-(4-Ethyl-1-piperazinyl)phenyl]-2-oxo-2H-1-benzopyran-3-carboxamide |
| Purity: | ≥98% (HPLC) |
β-catenin binder; inhibits Wnt signaling
| Chemical Name: | 2-Phenoxybenzoic acid-[(5-methyl-2-furanyl)methylene]hydrazide |
| Purity: | ≥99% (HPLC) |
Frizzled 4 allosteric agonist; exhibits biased signaling; preserves stemness
| Chemical Name: | 3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid |
| Purity: | ≥98% (HPLC) |
Wnt/β-catenin signaling inhibitor
| Purity: | ≥95% (HPLC) |
Selective peptide-based β-catenin Degrader (PROTAC®)
| Purity: | ≥95% (HPLC) |
endo-IWR 1 synthesized to Ancillary Material Grade
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% |
ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling
| Chemical Name: | (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol |
| Purity: | ≥98% (HPLC) |
Molecular glue Degrader of mutant β-catenin
| Chemical Name: | 2-[[4-[(2,6-Dichlorophenyl)thio]-1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinyl]carbonyl]-2,3-dihydro-1H-isoindole-4-carbonitrile |
| Purity: | ≥98% (HPLC) |
