CXCR2/IL-8RB Products
CXCR2/IL-8RB is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). Human CXCR2/IL-8RB is 360 amino acids (aa) in length with a predicted molecular weight of 41 kDa. The human protein shares 71% aa sequence identity with the mouse and rat protein. CXCR2/IL-8RB is expressed on neutrophils and activates neutrophil chemotaxis.
Similar to the closely related CXCR1/IL-8RA, CXCR2/IL-8RB binds and mediates CXCL8/IL-8-induced neutrophil activation. It also binds additional CXC chemokine ligands that contain an ELR aa motif. CXCR2/IL-8RB is implicated in neurological and pulmonary inflammatory diseases and injury. As such, it is a therapeutic target of interest in inflammatory disease and cancer.
Products:
287 results for "CXCR2/IL-8RB" in Products
287 results for "CXCR2/IL-8RB" in Products
CXCR2/IL-8RB Products
CXCR2/IL-8RB is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). Human CXCR2/IL-8RB is 360 amino acids (aa) in length with a predicted molecular weight of 41 kDa. The human protein shares 71% aa sequence identity with the mouse and rat protein. CXCR2/IL-8RB is expressed on neutrophils and activates neutrophil chemotaxis.
Similar to the closely related CXCR1/IL-8RA, CXCR2/IL-8RB binds and mediates CXCL8/IL-8-induced neutrophil activation. It also binds additional CXC chemokine ligands that contain an ELR aa motif. CXCR2/IL-8RB is implicated in neurological and pulmonary inflammatory diseases and injury. As such, it is a therapeutic target of interest in inflammatory disease and cancer.
Products:
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow, IHC, CyTOF-ready, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow, IHC, CyTOF-reported, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Applications: | AC |
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow |
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow |
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #5E8-C7-F10 |
| Applications: | IHC, Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #48311.211 |
| Applications: | Flow, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0212-24D12 |
| Applications: | IHC, Flow, CyTOF-ready, B/N |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow |
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #547 |
| Applications: | WB, ICC/IF |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |