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FGF basic/FGF2/bFGF Products

FGF basic/FGF2/bFGF is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic/FGF2/bFGF binds to FGFR1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGFR1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic/FGF2/bFGF with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.

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208 results for "FGF basic/FGF2/bFGF" in Products

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208 results for "FGF basic/FGF2/bFGF" in Products

FGF basic/FGF2/bFGF Products

FGF basic/FGF2/bFGF is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic/FGF2/bFGF binds to FGFR1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGFR1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic/FGF2/bFGF with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.

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Applications: BA
Applications: ELISA
Applications: BA

Intended for preclinical researchers who may transition to GMP FGF basic/FGF2 for their clinical work

Applications: ELISA
Applications: BA, BA

Analyzed by SEC-MALS

Applications: BA
Applications: ELISA
Applications: ELISA
Applications: BA
Applications: BA
Applications: BA
Applications: BA
Applications: WB, IHC, Neut
Reactivity: Human
Applications: BA
Applications: WB, Neut
Reactivity: Bovine
Applications: IHC, WB, ICC/IF, KO
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: BA
Catalog #: 133-FB
Applications: BA
Catalog #: MAB233
Reactivity: Human
Applications: IHC, ICC
Reactivity: Human
Applications: IHC, WB, ELISA
Reactivity: Human, Rat, Bovine, Equine
Applications: BA
Applications: BA
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