MMP-14/MT1-MMP Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
104 results for "MMP-14/MT1-MMP" in Products
Search
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Reviews
Gene Symbol
Brand
MMP-14/MT1-MMP Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
104 results for "MMP-14/MT1-MMP" in Products
Source: | E. coli |
Accession #: | P50281 |
Applications: | EnzAct |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | WB, Flow, IHC, IP, CyTOF-ready |
Recombinant Monoclonal Antibody.
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #3-F7 |
Applications: | IHC, WB, ICC/IF, Flow, IP |
Source: | NS0 |
Accession #: | P50281 |
Applications: | EnzAct |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #5H2 |
Applications: | WB, IHC, IP |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, IHC, CyTOF-ready |
Potent, broad spectrum MMP inhibitor
Alternate Names: | BB-94 |
Chemical Name: | (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide |
Purity: | ≥99% (HPLC) |
Broad spectrum MMP inhibitor
Alternate Names: | BB 2516,Marimistat |
Chemical Name: | (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide |
Purity: | ≥99% (HPLC) |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #128527 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #6A11D1 |
Applications: | IHC, WB, ELISA, Flow, CyTOF-ready |
Applications: | WB |
Histone deacetylase inhibitor
Chemical Name: | 3,4-Dichloro-N-(1-methylbutyl)benzamide |
Purity: | ≥99% (HPLC) |
Applications: | ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #S05-6H5 |
Applications: | IHC, WB |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #6T7L3 |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #LEM-2/15 |
Applications: | WB, ICC/IF, ELISA, B/N |