Hedgehog Signaling Inhibitors Products
13 results for "Hedgehog Signaling Inhibitors" in Products
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Hedgehog Signaling Inhibitors Products
13 results for "Hedgehog Signaling Inhibitors" in Products
Hedgehog signaling inhibitor; dynein inhibitor
| Chemical Name: | 2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile |
| Purity: | ≥98% (HPLC) |
GLI antagonist; inhibits Hedgehog (Hh) signaling
| Chemical Name: | 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine |
| Purity: | ≥98% (HPLC) |
Inhibitor of Hedgehog (Hh) signaling
| Chemical Name: | (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol |
| Purity: | ≥97% (HPLC) |
Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity
| Chemical Name: | N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine |
| Purity: | ≥98% (HPLC) |
Potent hedgehog pathway inhibitor
| Chemical Name: | 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide |
| Purity: | ≥98% (HPLC) |
Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase
| Chemical Name: | trans-N,N-bis[2-Chlorophenylmethyl]-1,4-cyclohexanedimethanamine dihydrochloride |
| Purity: | ≥99% (HPLC) |
Hedgehog (Hh) pathway antagonist, inhibits ciliogenesis; also inhibits dynein
| Alternate Names: | HPI-4 |
| Chemical Name: | 2,4-Dichloro-α-(3,4-4-oxo-2(1H)-quinazolinylidene)-β-oxobenzenepropanenitrile |
| Purity: | ≥98% (HPLC) |
Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein
| Chemical Name: | Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate |
| Purity: | ≥98% (HPLC) |
BET bromodomain Degrader (PROTAC®); also potent Hedgehog pathway inhibitor
| Chemical Name: | 2-Methoxyethyl 4-(3-((1-(6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate |
| Purity: | ≥98% (HPLC) |
Potent Smo antagonist
| Chemical Name: | N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide] |
| Purity: | ≥99% (HPLC) |
High affinity and selective Smoothened (Smo) receptor antagonist
| Chemical Name: | 1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl-1-piperazinyl]-3-(methylsulfonyl)-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent Smo antagonist
| Alternate Names: | glasdegib,PF-913 |
| Chemical Name: | 1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt |
| Purity: | ≥98% (HPLC) |
Potent Smoothened receptor antagonist
| Chemical Name: | rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide |
| Purity: | ≥98% (HPLC) |
