ICAM-1/CD54 Products
ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.
357 results for "ICAM-1/CD54" in Products
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ICAM-1/CD54 Products
ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.
357 results for "ICAM-1/CD54" in Products
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BBIG-I1 (11C81) |
| Applications: | WB, Simple Western, Flow, IP, AdBlk, +1 More |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, AdBlk |
| Source: | NS0 |
| Accession #: | Q3U8M7 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | CAA30051 |
| Applications: | BA |
| Sensitivity: | 0.254 ng/mL |
| Applications: | ELISA |
| Assay Range: | 1.56 - 50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ICAM1/8677R |
| Applications: | IHC |
| Sensitivity: | 0.053 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.625 - 40 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ICAM1/8247R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ICAM1/9379R |
| Applications: | IHC |
Simple Plex Human ICAM-1/CD54 assay kit for use on Ella instrument. Contains cartridge, sample diluent 000303, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
[[PRODUCT_PROMOS]]| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #1A29 |
| Applications: | IHC, WB, ICC/IF, Flow, Func, +2 More |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BBIG-I1 (11C81) |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | CAA30051 |
| Applications: | BA |
| Sensitivity: | 0.057 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.31 - 20 ng/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, AdBlk |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, AdBlk, ICC, KO |
| Reactivity: | Human |
| Details: | Goat Serum Polyclonal |
| Applications: | WB, IHC, ICC, KO |
| Sensitivity: | 4.1 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
Control for use with Human ICAM-1/CD54 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #14C11 |
| Applications: | WB, ICC |
Clone MEM-111 was used by HLDA to establish CD designation.
| Reactivity: | Human, Rat, Bovine |
| Details: | Mouse IgG2A Monoclonal Clone #MEM-111 |
| Applications: | IHC, WB, ELISA, Flow, CyTOF-ready |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
