Calnexin Products
Calnexin, an abundant approx. 90kDa integral protein of the endoplasmic reticulum, is also referred to as IP90, p88 and p90 (1). It consists of a large 50kDa N-terminal calcium-binding luminal domain, a single transmembrane helix and a short acidic cytoplasmic tail (2, 3). Unlike its ER counterparts which have a KDEL sequence on their Cterminus to ensure ER retention (4), calnexin has positively charged cytosolic residues that do the same thing (3). Most ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into mulit-subunit proteins. Calnexin together with calreticulin, plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglycosylated glycans (5, 6). Calnexin has also been shown to associate with the major histocompatability complex class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin (7).
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231 results for "Calnexin" in Products
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Calnexin Products
Calnexin, an abundant approx. 90kDa integral protein of the endoplasmic reticulum, is also referred to as IP90, p88 and p90 (1). It consists of a large 50kDa N-terminal calcium-binding luminal domain, a single transmembrane helix and a short acidic cytoplasmic tail (2, 3). Unlike its ER counterparts which have a KDEL sequence on their Cterminus to ensure ER retention (4), calnexin has positively charged cytosolic residues that do the same thing (3). Most ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into mulit-subunit proteins. Calnexin together with calreticulin, plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglycosylated glycans (5, 6). Calnexin has also been shown to associate with the major histocompatability complex class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin (7).
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231 results for "Calnexin" in Products
Applications: IHC, WB, ICC/IF, Flow, IP, Simple Western
Reactivity:
Human,
Mouse,
Rat,
Zebrafish,
Bovine, +9 More
Reactivity: | Human, Mouse, Rat, Zebrafish, Bovine, +9 More |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
Applications: IHC, WB, ICC/IF, Flow, IP, Simple Western
Reactivity:
Human,
Mouse,
Rat,
Hamster,
Zebrafish
Reactivity: | Human, Mouse, Rat, Hamster, Zebrafish |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #IE2.1C12 |
Applications: | IHC, WB, ICC/IF, Flow |
Reactivity: | Human, Mouse, Rat, Monkey |
Details: | Mouse IgG1 Monoclonal Clone #AF18 |
Applications: | IHC, WB, ICC/IF, IP, B/N |
Catalog #:
NBP1-97485
Applications: IHC, WB, ICC/IF, Flow, IP, MS, Simple Western
Reactivity:
Human,
Mouse,
Rat,
Canine,
Bovine, +10 More
Reactivity: | Human, Mouse, Rat, Canine, Bovine, +10 More |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, Flow, IP, +2 More |
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #1C2.2D11 |
Applications: | IHC, WB, ICC/IF, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2A Monoclonal Clone #1563 |
Applications: | WB, ICC/IF, IP, mIF |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human |
Details: | Mouse IgG2B Monoclonal Clone #3H4A7 |
Applications: | WB, ICC/IF, ELISA |
Catalog #:
NBP1-97476
Applications: IHC, WB, ICC/IF, IP, Single-Cell Western
Reactivity:
Human,
Mouse,
Rat,
Canine,
Bovine, +9 More
Reactivity: | Human, Mouse, Rat, Canine, Bovine, +9 More |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, IP, Single-Cell Western |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #CANX/1543 |
Applications: | IHC, WB, ELISA, MA |
Reactivity: | Human, Mouse, Opossum |
Details: | Goat IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA |
Reactivity: | Human, Rat (Negative) |
Details: | Mouse IgG2b Kappa Monoclonal Clone #CANX/1541 |
Applications: | IHC, WB, ICC/IF, ELISA |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human, Rat |
Details: | Rabbit IgG Monoclonal Clone #S07-2B1 |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CANX/9147R |
Applications: | ELISA, IHC, WB |
Applications: | ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #5S3U3 |
Applications: | WB |
Applications: | ELISA |
Applications: | PAGE |
Applications: | ELISA |